山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (3): 47-49.doi: 10.6040/j.issn.1673-3770.0.2017.171

• 变应性鼻结膜炎防治进展·论著 • 上一篇    下一篇

皮肤点刺呈阳性的变应性结膜炎与变应原相关性分析

阳珊,姜洋,金玉梅,李莹   

  1. 中国医学科学院北京协和医院眼科, 北京 100730
  • 收稿日期:2017-04-19 出版日期:2017-06-16 发布日期:2017-06-16
  • 通讯作者: 李莹. E-mail:liyingpumch@126.com

The relationship between allergens and allergic conjunctivitis identified by a positive skin prick test.

YANG Shan,  JIANG Yang, JIN  Yumei, LI Ying   

  1. Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2017-04-19 Online:2017-06-16 Published:2017-06-16

摘要: 目的 探究我国变应性结膜炎的常见变应原及变应原与变应性结膜炎临床特征相关性。 方法 收集就诊于北京协和医院的40例变应性结膜炎患者,均通过皮肤点刺试验检测出至少一种变应原。 结果 室内尘土、夏秋季花粉I、春季花粉II是最常见的变应原,同一患者可以同时被多种变应原致敏,且患者的瘙痒和球结膜充血评分随变应原阳性数量增加而加重;随着年龄增加,变应原阳性数量增加,且不同年龄阶段最常见的变应原存在差异;变应原阳性数量越多,合并全身其他变应性疾病风险增加。 结论 室内尘土和花粉是最常见的变应原,不同年龄阶段变应性结膜炎患者常见变应原存在差异,对多种变应原过敏的患者更易合并全身其他变应性疾病。

关键词: 变应原, 变应性结膜炎, 临床特点

Abstract: Objective To detect the causative allergens of allergic conjunctivitis and analyze the relationship between these allergens and the clinical characteristics of allergic conjunctivitis. Methods The symptoms and signs from 40 cases of allergic conjunctivitis were evaluated and analyzed; the causative allergens were detected in all the cases using skin prick testing. Results Dust and pollen were found to be the most common allergens. There was a positive correlation among positive detection rate of allergens,the severity of symptoms and the age of the patients. Conclusion Dust and pollen were the main causative allergens in allergic conjunctivitis, and the types of allergens were found to be associated with the age of the patients. A higher positive detection rate of allergens indicated a higher risk of other allergic diseases.

Key words: Clinical characteristics, Allergic conjunctivitis, Allergens

中图分类号: 

  • R777.31
[1] Leonardi A, Castegnaro A, Valerio AL, et al. Epidemiology of allergic conjunctivitis: clinical appearance and treatment patterns in a population-based study[J]. Curr Opin Allergy Clin Immunol, 2015, 15(5):482-488.
[2] 张晓霞,海鸥,乔少谊,等. 睫毛嫁接术致过敏性结膜炎16例[J]. 中国美容医学,2007,16(3):405.
[3] 刘祖国,肖启国.过敏性结膜炎的诊治[J].中华眼科杂志,2004,40(7):500-502.
[4] Baig R, Ali AW, Ali T, et al. Epidemiology of allergic conjunctivitis: clinical appearance and treatment patterns in a population-based study[J]. J Pak Med Assoc, 2010, 60(5):371-373.
[5] Abelson MB, George MA, Garofalo C. Differential diagnosis of ocular allergic disorders[J]. Ann Allergy, 1993, 70(2):95-105.
[6] 李莹,张潇,吕岚,等.过敏性结膜炎的流行病学及奥洛他定滴眼液开放性多中心治疗的初步效果[J].眼科,2008,17(3):166-170. LI Ying, ZHANG Xiao, L(¨overU)Lan, et al. Preliminary results of olopatadine hydrochloride in treating allergic conjunctivitis:a multicentral open trial[J]. Ophthalmol Chin, 2008, 17(3):166-170.
[7] 田桂花. 季节过敏性和常年过敏性结膜炎的变应原检测及治疗[J]. 临床眼科杂志, 2008, 16:345-346. TIAN Guihua. The detection and treatment of seasonal allergic conjunctivitis and perennial allergic conjunctivitis[J]. J Clin Ophthalmol, 2008, 16:345-346.
[8] Hong J, Zhong T, Li H, et al. Ambient air pollution, weather changes, and outpatient visits for allergic conjunctivitis: a retrospective registry study[J]. Sci Rep, 2016, 4(1):2385-2388.
[9] 穆剑, 王梅, 胡玉新,等. 不同年龄过敏性结膜炎变应原分析[J]. 岭南急诊医学杂志, 2013, 18(5):359-366. MU Jian, WANG Mei, HU Yuxin, et al. The allergen of allergic conjunctivitis in different age[J]. Lingnan J Emer Med, 2013, 18(5):359-366.
[1] 浦洪波,杜晓东. 无锡地区2 000例变应性鼻炎变应原检测结果分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 105-107.
[2] 王岩,师晓丽. 变态反应与儿童OSAHS的关系[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 14-18.
[3] 接英,卢红双. 变应性结膜炎的诊疗策略[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 31-36.
[4] 薛建荣,马敬,蒋星,胡志邦. 苏南地区儿童变应性鼻结膜炎临床研究[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 41-46.
[5] 吴中飞,怀德,桂晓钟,赵新,周文成,袁源,田慧琴,陆美萍,程雷. 苏皖健康人群血清免疫球蛋白E水平测定与分析[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 50-54.
[6] 朱新华. 变应性鼻炎冲击免疫治疗的临床应用[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 13-17.
[7] 程雷. 特异性免疫治疗是变应性鼻炎的一线疗法[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 1-2.
[8] 邰旭辉,杨昕,朱宝玉,曹鋐,褚彦玲,单晓东,姜宇. 辽宁地区2 883例变应性鼻炎患者变应原分布特征[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 39-42.
[9] 袁源,吴中飞,巢长江,陆美萍,田慧琴,程雷. 健康成人血清总IgE和变应原特异性IgE检测及意义[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 34-38.
[10] 李勇. 变应性鼻炎免疫治疗共识及相关进展[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 15-21.
[11] 阎艾慧,韩佳利. 变应性鼻炎的临床特点与诊断[J]. 山东大学耳鼻喉眼学报, 2016, 30(4): 7-9.
[12] 黎柱杨, 王春, 叶涛, 吴伟铭, 陈紫红, 邓燕姬, 钟金英, 董英花. 广西梧州地区变应性鼻炎患者的吸入性变应原分布特点[J]. 山东大学耳鼻喉眼学报, 2015, 29(1): 35-37.
[13] 何本超,徐必生,程琦,胡晶,李健勇 . 天门地区变应性鼻炎吸入性变应原皮肤点刺试验结果分析[J]. 山东大学耳鼻喉眼学报, 2014, 28(3): 10-12.
[14] 戴伟利,张杰,张亚梅. 北京地区1~12岁儿童变应性鼻炎变应原谱分析[J]. 山东大学耳鼻喉眼学报, 2014, 28(1): 39-45.
[15] 赵莉1,杨燕2,史丽2. 山东省变应性鼻炎患者变应原皮肤点刺试验结果分析[J]. 山东大学耳鼻喉眼学报, 2013, 27(3): 22-24.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!